• Author Q&A Series: H pylori-associated Gastric Cancer

Author Q&A Series: H pylori-associated Gastric Cancer

Gastric tumors and tissues from humans and mice accumulate somatic mutations in various genes in the gastric mucosa upon Helicobacter pylori infection, researchers report in the August issue of Gastroenterology. In the study, Takahiro Shimizu et al. show that increased cytidine deaminase activity in these tissues promotes the accumulation of these mutations and might

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Origins of Gastric Cancer

Gastric tumors can arise from a single mutation in a single stomach gland, according to Lydia Gutierrez-Gonzalez et al. in the April issue of Gastroenterology. To study how gastric dysplasias form and expand, Gutierrez-Gonzalez et al. analyzed 23 samples of gastric epithelium from patients who received surgery for gastric adenocarcinoma

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